Tender Details

Liquid Chromatography-Mass Spectrometry (LC-MS) system

Business Name

QIMR Berghofer Medical Research Institute

VP Reference #

VP473188

Buyers Reference #

2025 141

Opens

Monday 11 August 2025 (E. Australia Standard Time)

Closes

Wednesday 27 August 2025 05:00 PM (E. Australia Standard Time) CLOSED

Supplier query cut-off

Wednesday 27 August 2025 05:00 PM (E. Australia Standard Time)

Expected decision

Wednesday 17 September 2025 (E. Australia Standard Time)

Buyer Details

Business Name

QIMR Berghofer Medical Research Institute

Location

300 Herston Rd
Herston, Queensland 4006
Australia

WebSite:

http://www.qimrberghofer.edu.au

Business Info

At QIMR Berghofer, we seek to discover, diagnose and deliver better treatments for some of the world’s deadliest diseases.

Contact Details

The buyer has elected to have their personal and contact details hidden. These details will be revealed at the buyers discretion.

What the buyer is requesting

Details

The Queensland Institute of Medical Research (QIMR Berghofer), 300 Herston Road, Brisbane, QLD 4006, is seeking to procure a state-of-the-art Liquid Chromatography-Mass Spectrometry (LC-MS) system to enhance its capabilities in advanced proteomics and related omics research. This acquisition is critical to supporting high-impact biomedical research, particularly in the areas of post-translational modification (PTM) analysis, targeted proteomics, and metabolomics workflows.

The LC-MS system must deliver best-in-class analytical performance within a defined budget, with robust support for bottom-up proteomics workflows, high-throughput data acquisition, and seamless integration with existing bioinformatics infrastructure. The system will be used across a range of research applications, requiring high sensitivity, reproducibility, and flexibility in both chromatography and mass spectrometry functions.

Background information / Compatibility requirements

Details

This procurement encompasses the supply, installation, commissioning, and support of a fully integrated LC-MS system.

Desired Outcomes ('Nice to haves', Conditions & Warranties, SLA's, Project benefits)

Details

• Functional and Performance Requirements:

- High-resolution proteomics analysis, including PTM and phosphoproteomics

- Efficient and scalable data acquisition, processing, and storage

- Proven performance metrics across varied sample types and loading amounts

- Compatibility with existing laboratory workflows and data systems

• Technical Specifications:

- Detailed specifications for chromatography and mass spectrometry components

- Support for multiple acquisition modes (DDA, DIA, PRM)

- Advanced analytical metrics including FDR, CV%, sensitivity, and dynamic range

- Optional ion mobility capabilities and top-down proteomics support

• Compliance and Standards:

- Adherence to relevant Australian and international safety and technical standards, including AS/NZS 3000:2018, AS/NZS 61010.1, and ISO/IEC 17025:2017 (where applicable)

• Consumables and Lifecycle Support:

- Clear identification of required consumables, proprietary items, and volume discount options

- Comprehensive warranty provisions, with preference for commencement post-acceptance testing

- Options for extended warranty and whole-of-life support

• Acceptance Testing and Commissioning:

- A certified and mutually agreed acceptance testing process

- Documentation for IQ/OQ/PQ validation

- Flexibility for QIMR Berghofer to conduct additional performance verification testing

Questions asked by the buyer

Question 1 - [Required]

4.2.1.1 Please provide the latest verifiable data for the instrumentation, including metrics relating to the number of protein groups, peptide groups, phosphopeptides and class I phosphosites achievable.

Question 2 - [Required]

4.2.1.2 Provide all experimental parameter information, including but not limited to:
• The source of biological material used to generate the data
• The amount of peptide or enriched sample introduced to the system (ideally across a wide range of loading amounts to enable direct comparison)
• The total run time (or SPD) and gradient length if there is relevant dead time (ideally example chromatograms would be included)
• Details of the chromatography method such as LC system, column, flow rate, temperature and so on
• Details of the MS operation such as resolution, mass range used, data acquisition mode, isolation window width, software used to process data and any other relevant parameters
• Any statistical metrics applicable to the data, such as FDR, CV%

Question 3 - [Required]

4.2.1.3 What other relevant capabilities of the instrument for other analysis modes (top-down, PRM, PTM analysis, metabolomics, and lipidomics), fragmentation options, ion mobility options, data processing/analysis software, storage solutions.

Question 4 - [Required]

4.2.1.3 Any other information deemed worthy of inclusion in the tender.

Question 5

4.2.1.4 Submissions will be evaluated based on:
• Analytical performance and throughput
• Breadth of application (proteomics, metabolomics, etc.)
• Ease of use and software integration
• Support, training, and warranty
• Value for money within the allocated budget

Supplier lists selected

Lists

Lab, Measure, Observe & Test Equip

Categories selected

Categories

Laboratory & Measuring & Observing & Testing Equip
1: Measuring & Observing & Testing Equipment

Regions of Service

Locations

Australian Capital Territory
1: ACT (all other areas)
2: Canberra
3: Offshore (ACT)
New South Wales
1: Offshore (NSW)
2: Sydney
Queensland
1: Brisbane
2: Gold Coast
3: Offshore (QLD)
4: Sunshine Coast
Victoria
1: Melbourne
2: Offshore (VIC)
Western Australia
1: Offshore (WA)
2: Perth

Regions of service locations also include areas outside of Australia.

Information requested by others

19/Aug/2025 09:51 AM

Question:
Sample Analysis Request

If you require sample analysis, are we able to get more information regarding the number and type of samples (including QC’s and blanks). If you wish to run and the criteria that will use for evaluation?

We will need this information in order to recommend the best suited site to run the analysis. We will also need to know how the samples are being prepared

Answered on 21/Aug/2025 09:24 AM:

“In the event of a comparative sample analysis being required, we would provide 20-25 serum sample extracts (unfractionated) and a pooled QC sample, processed for global (bottom-up) proteomics, ideally using a 30-minute run for direct comparison across vendors. These samples have previously had data acquired on our existing instrumentation (Thermo QE HF-X) and this would therefore provide a direct comparison with current capability as well as across competing vendor offerings. The evaluation criteria used will include: number of protein groups obtained, number of peptide groups obtained, number of unique variables (if any), strength of group separation (if any), CV% of QC output, etc. The sample set will likely comprise 4 or 5 groups of 5 biological replicates”

Updates made to this Request

Updates

None...